Star Alliance member SWISS is running a nice sale resulting in great prices for flights from Italy. You can book tickets for flights to São Paulo in South America’s largest country, starting at only €369. Availability is fantastic throughout the year. Adding a piece of luggage will increase the ticket price by roughly 45€ – still leaving you with a great price.
The fare is also available from Naples, Florence, Brindisi, Bari, Olbia and Palermo. However, service to / from some of these airports is limited to the summer schedule